| Date | Opponent | Score | Record |
| October 16, 2010 | Florida State | W 15-9 | 1 - 0 |
| October 16, 2010 | Wake Forest | W 15-1 | 2 - 0 |
| October 16, 2010 | NC State | W 15-3 | 3 - 0 |
| October 16, 2010 | North Carolina | W 15-3 | 4 - 0 |
| October 17, 2010 | Clemson | W 15-5 | 5 - 0 |
| October 17, 2010 | Virginia | L 14-16 | 5 - 1 |
| October 17, 2010 | Duke | W 15-8 | 6 - 1 |
| October 17, 2010 | Virginia | L 10-15 | 6 - 2 |
| November 20, 2010 | Tennessee | W 15-6 | 7 - 2 |
| November 20, 2010 | Pittsburgh | W 16-15 | 8 - 2 |
| November 20, 2010 | James Madison | W 15-3 | 9 - 2 |
| November 20, 2010 | Brandies | W 15-3 | 10 - 2 |
| November 21, 2010 | Virginia | W 15-7 | 11 - 2 |
| November 21, 2010 | UCONN | W 15-8 | 12 - 2 |
| November 21, 2010 | Dartmouth | L 12-15 | 12 - 3 |
| November 21, 2010 | Pittsburgh | L 7-15 | 12 - 4 |
| Start Date | Tournament | Seed | Result | |
| November 20, 2010 | 2010 UOA College Nationals | 5 | 2 | Tweets (99) |
| October 16, 2010 | 2010 UOA ACC 8s | 4 | 2 | Tweets (45) |
