| Date | Opponent | Score | Record |
| November 13, 2010 | Georgetown | 0-0 | 0 - 0 |
| November 13, 2010 | Millersville | 0-0 | 0 - 0 |
| November 13, 2010 | NYU | 0-0 | 0 - 0 |
| November 14, 2010 | Johns Hopkins | W 13-4 | 1 - 0 |
| November 14, 2010 | Shippensburg | W 9-7 | 2 - 0 |
| November 14, 2010 | William and Mary | W 13-7 | 3 - 0 |
| November 14, 2010 | Millersville | W 15-9 | 4 - 0 |
| March 19, 2011 | Indiana (Pennsylvania) | W 15-2 | 5 - 0 |
| March 19, 2011 | St Joseph's | W 15-1 | 6 - 0 |
| March 19, 2011 | Lehigh | W 15-5 | 7 - 0 |
| March 19, 2011 | Millersville | W 15-11 | 8 - 0 |
| March 20, 2011 | Ursinus | W 15-1 | 9 - 0 |
| March 20, 2011 | Lehigh | W 15-2 | 10 - 0 |
| March 20, 2011 | Carnegie-Mellon | W 15-3 | 11 - 0 |
| March 20, 2011 | Georgetown | W 12-8 | 12 - 0 |
| April 23, 2011 | Carnegie-Mellon | W 11-7 | 13 - 0 |
| April 23, 2011 | Indiana (Pennsylvania) | W 13-4 | 14 - 0 |
| April 23, 2011 | Pittsburgh | L 9-13 | 14 - 1 |
| April 23, 2011 | West Virginia | W 13-1 | 15 - 1 |
| April 30, 2011 | Kenyon | W 12-11 | 16 - 1 |
| April 30, 2011 | Edinboro | W 15-4 | 17 - 1 |
| April 30, 2011 | Shippensburg | W 15-4 | 18 - 1 |
| May 1, 2011 | Cincinatti | W 15-11 | 19 - 1 |
| May 1, 2011 | Ohio State | W 15-9 | 20 - 1 |
| May 1, 2011 | Pittsburgh | L 9-15 | 20 - 2 |
